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Tesla, Inc. engages in the design, development, manufacture, and sale of electric vehicles and energy generation and storage systems. It operates through the Automotive and Energy Generation and Storage segments. The Automotive segment includes the design, development, manufacture, sale, and lease of electric vehicles as well as sales of automotive regulatory credits. The Energy Generation and Storage segment is involved in the design, manufacture, installation, sale, and lease of solar energy generation, energy storage products, and related services and sales of solar energy systems incentives. The company was founded by Jeffrey B. Straubel, Elon Reeve Musk, Martin Eberhard, and Marc Tarpenning on July 1, 2003 and is headquartered in Austin, TX.

Tesla Inc

Tesla is trending after a mixed Q4 earnings report, with declining auto sales overshadowed by Elon Musk's strategic pivot to discontinue Model S and X production in favor of aggressively pursuing AI, robotics, and robotaxi development, including a significant investment in xAI; this bold move is fueling intense community discussion, dividing those bullish on "amazing abundance" and critics citing unfulfilled promises and high valuations.

SPDR Gold Trust - SPDR Gold Shares

SPDR Gold Shares ETF

GLD is experiencing a historic, near-parabolic ascent to new all-time highs, propelled by significant institutional and central bank accumulation, ongoing inflation concerns, and a pervasive narrative of a weakening US dollar. While many in the community view this as a crucial safe-haven hedge against global instability, a growing chorus of bears anticipates an imminent 'blow-off top' and sharp correction, questioning the sustainability of such extreme upward momentum.

USA Rare Earth, Inc. is domestic supplier of rare earth magnets and heavy rare earth elements. It is developing a vertically integrated, domestic supply chain for rare earth element magnet production, with a facility in Stillwater, Oklahoma, and mining rights to the Round Top heavy rare earth and critical minerals deposit in West Texas. The company was founded in May 2019 and is headquartered in Stillwater, OK.

USA Rare Earth Inc. - Ordinary Shares - Class A

USA Rare Earth Inc

USA Rare Earth is trending amid a sector-wide sell-off sparked by a report suggesting the government is stepping back from critical mineral price floors, yet many in the community believe this is an overreaction given USAR's recent $1.6 billion federal financing deal and its focus on high-value rare earths that may not require such guarantees.

Critical Metals Corp. engages in the mining, exploration, and development of lithium metals. It owns Wolfsberg Project and Tanbreez Project. The company was founded on October 24, 2022 and is headquartered in British Virgin Islands.

Critical Metals Corp.

A Reuters report on the US reportedly abandoning critical minerals price floors caused a significant sector-wide sell-off for Critical Metals Corp., sparking intense community debate. While some panicked, many are aggressively "buying the dip," citing the CEO's affirmation that their heavy rare earth project doesn't require price support and anticipating a strong rebound leading into the February 4th Critical Minerals Summit.

Meta Platforms, Inc. engages in the development of social media applications. It builds technology that helps people connect and share, find communities, and grow businesses. It operates through the Family of Apps (FoA) and Reality Labs (RL) segments. The FoA segment consists of Facebook, Instagram, Messenger, WhatsApp, and other services. The RL segment includes augmented, mixed and virtual reality related consumer hardware, software, and content. The company was founded by Mark Elliot Zuckerberg, Dustin Moskovitz, Chris R. Hughes, Andrew McCollum, and Eduardo P. Saverin on February 4, 2004, and is headquartered in Menlo Park, CA.

Meta Platforms Inc - Ordinary Shares - Class A

Meta Platforms Inc

Meta Platforms is surging after delivering a strong earnings report, driven by robust advertising growth and ambitious AI infrastructure investments, sparking community discussion over the significant capital expenditures and the company's new dividend.

MP Materials Corp. engages in the production and marketing of rare earth specialty materials. It operates through the Materials and Magnetics segments. The Materials segment focuses on the operation of Mountain Pass, which produces refined rare earth oxides and related products, as well as rare earth concentrate products. The Magnetics segment is involved in the operation of Independence Facility, where the company began production of magnetic precursor products. The company was founded by James Henry Litinsky and Michael Rosenthal in 2017 and is headquartered in Las Vegas, NV.

MP Materials Corporation

MP Materials is trending due to market reactions to a Reuters report on U.S. critical mineral price floor policy, despite clarifications that the company's existing government-backed price floor remains intact. The community is actively discussing perceived market manipulation and "buying the dip" amidst broader sector volatility driven by national security and domestic supply chain narratives.

United States Antimony Corp. engages in the extraction, processing and sale of antimony, zeolite, silver, and gold products. It operates through the following segments: United States Antimony Operations, Mexican Antimony Operations, Precious Metals Recovery, and United States Zeolite Operations. The company was founded by John C. Lawrence in June 1968 and is headquartered in Thompson Falls, MT.

United States Antimony Corp.

United States Antimony Corp

United States Antimony (UAMY) is experiencing sector-wide volatility after reports indicated the US government is stepping back from critical mineral price floors, but many in the community are seizing the dip, confident in the company's existing government contracts, financial independence as the sole US antimony producer, and recent bullish analyst ratings.

Microsoft Corp. engages in the development and support of software, services, devices, and solutions. It operates through the following segments: Productivity and Business Processes, Intelligent Cloud, and More Personal Computing. The Productivity and Business Processes segment is composed of products and services relating to productivity, communication, and information services such as Office Commercial, Office Consumer, LinkedIn, and Dynamics business solutions. The Intelligent Cloud segment consists of public, private, and hybrid server products and cloud services for businesses and developers, as well as enterprise and partner services. The More Personal Computing segment refers to products and services including Windows operating system, Windows cloud services, Surface, HoloLens, personal computer accessories, Xbox hardware, Xbox Cloud Gaming, Microsoft News, and Microsoft Edge. The company was founded by Paul Gardner Allen and William Henry Gates, III in 1975 and is headquartered in Redmond, WA.

Microsoft Corporation

Microsoft Corp

Microsoft is trending after its earnings report, where a beat on top and bottom lines was overshadowed by concerns over slowing Azure growth and significantly higher capital expenditures for AI, pressuring margins. This has ignited community debate, with many viewing it as an "oversold" buying opportunity while others contend it signals the "AI bubble" is straining under the immense capital investment required for limited immediate returns.

Carvana Co. is a holding company and an eCommerce platform, which engages in the buying and selling of used cars. The company was founded by Ernest Garcia, III, Benjamin Huston and Ryan Keeton in 2012 and is headquartered in Tempe, AZ.

Carvana Co. - Ordinary Shares - Class A

Carvana Co.

Carvana is trending following a Gotham City Research short report that alleges substantial accounting irregularities and undisclosed reliance on related parties, igniting a fierce debate among investors, with some declaring it a 'Ponzi scheme' while others dismiss it as a 'hit piece' and expect a rebound.

TMC the metals co., Inc. is a deep-sea minerals exploration company focused on the collection and processing of polymetallic nodules found on the seafloor in international waters of the Clarion Clipperton Zone in the Pacific Ocean (CCZ). These nodules contain high grades of four metals (nickel, copper, cobalt, manganese) which can be used as (i) feedstock for battery cathode precursors (nickel, cobalt and manganese sulfates, or intermediate nickel-copper-cobalt matte) for electric vehicles (EV) and renewable energy storage markets, (ii) copper cathode for EV wiring, energy transmission and other applications and (iii) manganese silicate for manganese alloy production required for steel production. The company was founded in 2021 and is headquartered in Vancouver, Canada.

TMC the metals company Inc

TMC is trending as the market reacts to a Reuters report signaling the administration's shift away from critical mineral price guarantees, initially causing a sector-wide dip. However, the community strongly believes TMC's unique cost structure means it doesn't need price floors, with many calling the dip a short-driven shakeout ahead of imminent permit approvals and a crucial critical minerals conference.

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<ul class="summary-bullets"><li>The company said that the FDA hold has impacted two experimental gene therapies, RGX-111 and RGX-121.</li><li>REGENXBIO added that the tumor was identified during a routine brain MRI of an asymptomatic five-year-old participant in its RGX-111 trial.</li><li>The company said that the participant had received intracisternal RGX-111 four years prior.</li></ul>REGENXBIO Inc.’s (RGNX) shares tumbled more than 29% in Wednesday’s&nbsp;opening trade after the company announced an update from the U.S. Food and Drug Administration (FDA).REGENXBIO stated that the FDA has placed a clinical hold on the company’s experimental gene therapy program for the treatment of rare childhood diseases.The company said that the FDA hold has impacted two experimental gene therapies, RGX-111 and RGX-121.<h2 class="st-heading-2">Why Did FDA Place A Clinical Hold?</h2>REGENXBIO stated that the FDA’s clinical hold was placed after a brain tumor was found in one patient in the trial.The company added that the tumor was identified during a routine brain magnetic resonance imaging (MRI) of an asymptomatic five-year-old participant in its RGX-111 trial. REGENXBIO said that the participant had received intracisternal RGX-111 four years prior.The company said that an investigation into whether this serious adverse event (SAE) is drug-related is ongoing, and that causality has not been established yet.While the SAE involved a patient in the RGX-111 trial, the FDA has also placed a hold on the RGX-121 gene therapy, citing the similarities in products, study populations, and shared risk between the clinical studies, the company said.“These are separate therapies, and the positive safety profile of RGX-121 in more than 30 patients treated, including those dosed nearly seven years ago, remains unchanged,” said REGENXBIO CEO Curran Simpson.<h2 class="st-heading-2">What Did REGENXBIO’s Experimental Therapies Treat?</h2>The RGX-111 gene therapy is aimed at treating MPS I, also known as Hurler syndrome. This is a genetic disorder that results in the buildup of large sugar molecules in lysosomes, causing damage to several organ systems.The RGX-121 gene therapy is aimed at treating MPS II, also known as&nbsp;Hunter syndrome, which results in the buildup of large sugar molecules in body tissues. This causes abnormalities in body organs, including the heart, skeleton, and respiratory system.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits around&nbsp;<a href="https://stocktwits.com/symbol/RGNX">REGENXBIO</a> was in the ‘bearish’ territory, with message volumes at ‘extremely high’ levels at the time of writing.One user thinks that the stock decline is an “overreaction.”<stembedurl>https://stocktwits.com/Longbuy1/message/643122172</stembedurl><a href="https://stocktwits.com/symbol/RGNX">RGNX stock</a> is down 34% year-to-date, but up 25% over the past 12 months.Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/trump-signals-military-escalation-toward-iran-as-markets-brace-for-big-tech-earnings-fed-decision/cmygPjOR40T">Trump Signals Military Escalation Toward Iran As Markets Brace For Big Tech Earnings, Fed Decision</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Trading digital board showing the data on global stock market crash. | Image source: Getty Images

RGNX Stock Is Falling Today — What Is The FDA Update On REGENXBIO's Gene Therapy?

REGENXBIO stated that the FDA has placed a clinical hold on the company’s experimental gene therapy program for the treatment of rare childhood diseases.

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<ul class="summary-bullets"><li>Florida Atlantic University commits $20 million to purchase and install a D-Wave Advantage2 annealing system.</li><li>D-Wave to establish its new corporate headquarters at the Boca Raton Innovation Center.</li><li>D-Wave is expected to showcase new hybrid solver capabilities using machine learning in quantum workflows at the Qubits 2026 conference later on Tuesday.</li></ul>Shares of D-Wave Quantum Inc. (QBTS) drew significant retail interest on Tuesday morning after rising over 5% in pre-market trading, fueled by fresh updates including a defense partnership and a deal with Florida Atlantic University.D-Wave Quantum announced that Florida Atlantic University (FAU) has committed $20 million to purchase and install a D-Wave Advantage2 annealing system at its Boca Raton campus, with deployment expected later in 2026.&nbsp;This system will serve as the foundation for a new collaboration between D-Wave and FAU, which could include a Quantum Applications Academy and support for research, training, and workforce development initiatives.&nbsp;D-Wave will also establish its new corporate headquarters at the Boca Raton Innovation Center.<h2 class="st-heading-2">More Collaborations</h2>In a separate announcement, D-Wave revealed a collaboration with Davidson Technologies and defense company Anduril Industries to develop quantum-classical hybrid applications for complex U.S. air and missile defense scenarios.Initial proof-of-concept tests using D-Wave’s Stride hybrid solver on the Advantage2 system demonstrated up to 10x faster solutions, a 9-12% improvement in threat mitigation, and the ability to intercept 45-60 additional missiles in a simulated 500-missile attack.The collaboration will expand to other defense challenges, including logistics, manufacturing, cyber defense, and course-of-action planning, the company added.At D-Wave’s Qubits 2026 conference later on Tuesday, the company is expected to showcase new hybrid solver capabilities using machine learning in quantum workflows, as well as progress on its technologies following the acquisition of Quantum Circuits earlier this month.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits turned ‘bullish’ from ‘neutral’ a day earlier, amid ‘high’ message volumes. <a href="https://stocktwits.com/symbol/QBTS">QBTS</a> was among the top trending tickers on the platform.<img src="https://news.stocktwits-cdn.com/QBTS_jpg_8dd9a289c0.webp" alt="QBTS.jpg">One Stocktwits user sounded skeptical and highlighted the stock’s current valuation.<stembedurl>https://stocktwits.com/Shelby007/message/642988665</stembedurl>The stock has gained more than 300% over the past year, even as year-to-date declines stand at around 12%.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/ups-stock-rises-q4-beat-strong-2026-guidance/cmyavvvR4Le">UPS Stock Rises Pre-Market On Upbeat Guidance – CEO Calls 2026 As Inflection Year After Amazon Pullback</a> For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, D-Wave Systems Inc. logo of a Canadian quantum computing company is seen on a smartphone screen.

What Triggered QBTS Stock’s Pre-Market Rally Today?

The company tied up with Davidson Technologies and defense company Anduril Industries to develop quantum-classical hybrid applications for U.S. air and missile defense scenarios.

<ul class="summary-bullets"><li>The revised label provides clearer starting-dose guidance for adult patients switching from multiple daily injections or insulin pump therapy.</li><li>The update is supported by clinical results from the Dose Optimization study and the INHALE-3 trial.</li><li>Previously, MannKind filed a supplemental FDA application to expand Afrezza’s use to patients aged four to 17, with a decision anticipated by May 29, 2026.</li></ul>Shares of MannKind Corp. (MNKD) gained more than 7% in pre-market trading on Monday after the company announced that the U.S. Food and Drug Administration (FDA) approved an update to the prescribing information for Afrezza, its inhaled mealtime insulin used to improve glycemic control in adult patients with diabetes mellitus.The revised label provides clearer starting-dose guidance for adult patients switching from multiple daily injections or insulin pump therapy. The update is supported by clinical results from the Dose Optimization study and the INHALE-3 trial, which showed significantly improved post-meal glucose control after conversion to Afrezza, as recommended by the new dosing recommendations.“We expect that this label update will help support healthcare providers by providing clearer starting dose guidance when transitioning patients to inhaled insulin from subcutaneous mealtime insulin—whether injections or insulin pumps. We believe this refinement to the label helps support appropriate initiation of therapy while reinforcing Afrezza’s established clinical profile,” said Kevin Kaiserman, Senior Vice President, Therapeutic Area Head, Diabetes at MannKind Corporation.&nbsp;<h2 class="st-heading-2">Q3 Revenue Boosted By Afrezza Sales</h2>In November, the company posted a 17% increase in third-quarter (Q3) total revenue to $82.13 million, driven by strong growth in sales of its Afrezza inhaled insulin. Afrezza revenue climbed 23% to $18.5 million, supported by higher pricing and rising demand, while royalty income rose to $33.3 million.MannKind also submitted a supplemental application to the FDA seeking approval of Afrezza for patients aged four to 17. A regulatory decision is expected by May 29, 2026.<h2 class="st-heading-2">How Did Retail React?</h2>Retail sentiment for <a href="https://stocktwits.com/symbol/MNKD">MNKD</a> on Stocktwits remained in the ‘bullish’ zone over the past 24 hours, accompanied by ‘high’ message volumes. MNKD was among the top trending tickers at the time of writing.<figure class="image"><img src="https://news.stocktwits-cdn.com/MNKD_jpg_fd37ecdc2d.webp" alt="MNKD.jpg" width="930" height="85"><figcaption>MNKD's Sentiment Meter and Message Volumes at Premarket on Jan. 26, 2026 | Source: Stocktwits</figcaption></figure>Meanwhile, one user didn’t see the FDA update as a major catalyst.<stembedurl>https://stocktwits.com/firefox2778/message/642859216</stembedurl>The stock has declined around 4.7% year-to-date and over 10.5% in the past year.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/ag-asml-hl-stocks-soar-silver-prices-record-high-110/cmy78kuR4WC">AG, ASM, HL Stocks Soar Pre-Market As Silver Blasts Past $110</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Mannkind Corp and the company's inhalable insulin product. Company employee demonstrating how the device is used. (Photo by Lawrence K. Ho/Los Angeles Times via Getty Images)

Why Did MNKD Stock Jump Over 7% In Pre-Market Today?

The U.S. FDA approved an update to the prescribing information for Afrezza inhalation powder to treat adults with diabetes mellitus.

MNKD Stock Gets A Pre-Market Boost From FDA Label Revision For Afrezza

Should iShares Russell 2000 ETF (IWM) Be on Your Investing Radar?

<ul class="summary-bullets"><li>The offering includes 34.8 million shares at $5.75, the stock’s closing price on Tuesday.</li><li>Medtronic’s investment is expected to give it a post-offering ownership stake of between 16% and 19.99%.</li><li>Proceeds from the transactions will be used to support Anteris’ clinical strategy, including&nbsp; R&amp;D at v2vmedtech.</li></ul>Shares of Anteris Technologies Global Corp. (AVR) jumped sharply in pre-market trading on Wednesday after the structural heart specialist unveiled a $200 million equity raise alongside a sizable strategic investment from healthcare technology heavyweight Medtronic.<a href="https://stocktwits.com/symbol/AVR">AVR shares</a> were up around 17% at the time of writing and were on track to open at their highest levels since March 2025.Anteris announced a proposal to raise $200 million via a public offering of its common stock and grant underwriters a 30-day option to purchase up to an additional $30 million of shares at the public offering price.In a separate release, the company said the offer is to sell around 34.8 million shares at $5.75, the stock’s closing price on Tuesday.<h2 class="st-heading-2">Medtronic Investment</h2>Alongside the public offering, Anteris entered into a stock purchase agreement with Medtronic plc (MDT). Under the deal, Medtronic, through a wholly owned unit, will invest up to $90 million in Anteris common stock via a private placement priced in line with the public offering. The transaction is expected to give Medtronic a post-offering ownership stake of between 16% and 19.99% in Anteris.Proceeds from the transactions will be used to support Anteris’ clinical strategy, including continued patient recruitment and execution of the global PARADIGM pivotal trial for the DurAVR Transcatheter Heart Valve (THV) in severe aortic stenosis, expanding manufacturing capacity, and funding ongoing research and development (R&amp;D) at v2vmedtech, a privately owned medical technology company.The DurAVR THV is a biomimetic valve designed to mimic the performance of a healthy aortic valve.&nbsp;<h2 class="st-heading-2">What Is Retail Saying?</h2>On Wednesday, retail sentiment for AVR flipped to ‘extremely bullish’ from ‘bearish’ a day earlier, while message volumes increased to ‘extremely high’ from ‘normal’ on Stocktwits. AVR was among the top trending tickers on the platform at the time of writing.<img src="https://news.stocktwits-cdn.com/AVR_jpg_6c056947d5.webp" alt="AVR.jpg">One user expects the stock to hit $20 on the ‘bullish news’.<stembedurl>https://stocktwits.com/Redrooster79/message/642383722</stembedurl>However, another user was slightly skeptical about the dilution.<stembedurl>https://stocktwits.com/Rvazstocksfl/message/642363903</stembedurl>AVR stock has declined more than 4% over the past year but has gained around 12% so far in 2026.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-is-nvidia-stock-rising-in-premarket-today/cmUDZxrR4Oz">Why Is Nvidia Stock Rising In Premarket Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Rising chart and reflection of business buildings: stock photo courtesy of Yuichiro Chino via Getty Images

Why Did AVR Stock Surge Pre-Market Today? 

The company unveiled a $200 million dilution alongside a $90 million investment from healthcare technology heavyweight Medtronic.

AVR Stock Pops Pre-Market: Medtronic Backs $200M Capital Raise To Fund Key Trial

Relative Strength: Identifying Alpha in Market Weakness

The stocks that refuse to drop in a tough market are often the ones that will lead the next leg higher. By utilizing relative strength, investors can identify the best long opportunities. 

<ul class="summary-bullets"><li>The deal provides Novavax with an upfront payment of $30 million, along with the opportunity to earn up to $500 million in additional development and sales milestones.</li><li>Matrix-M adjuvant is a proprietary vaccine ingredient, used in several marketed vaccines to improve effectiveness and help the immune system better recognize and remember disease targets.</li><li>Novavax is eligible to receive tiered royalties in the high mid-single digit range on sales of any Pfizer products that use Matrix-M.</li></ul>Novavax, Inc. (NVAX) shares climbed 6% higher in pre-market trading on Tuesday after the company signed a licensing agreement with Pfizer, granting the pharmaceutical giant non-exclusive rights to use Novavax’s Matrix-M adjuvant in up to two disease areas.Matrix-M adjuvant is a proprietary vaccine ingredient that improves the body’s immune response. It is made from naturally derived compounds and is used in several marketed vaccines to improve effectiveness and help the immune system better recognize and remember disease targets, according to Novavax.<h2 class="st-heading-2">What Is The Novovax-Pfizer Deal?</h2>The deal provides Novavax with an upfront payment of $30 million, along with the opportunity to earn up to $500 million in additional development and sales milestones. Novavax is also eligible to receive tiered royalties in the high mid-single digit range on sales of any Pfizer products that use Matrix-M.Under the agreement, Pfizer will take full responsibility for the development and commercialization of its products, while Novavax will supply the Matrix-M adjuvant. The partnership strengthens Novavax’s long-term revenue potential.This comes after Novavax completed the transfer of U.S. and European marketing authorizations for its COVID-19 vaccine, Nuvaxovid, to Sanofi in November. The move resulted in a second $25 million milestone payment to Novavax, following the completion of the European Union marketing authorization transfer in October 2025.Novavax is expected to receive additional milestone payments and royalties tied to Nuvaxovid, Sanofi-developed combination products, and new vaccines that use Novavax’s Matrix-M adjuvant. Novavax also has long-standing partnerships with Japan’s Takeda and the Serum Institute of India.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment for <a href="https://stocktwits.com/symbol/NVAX">NVAX</a> on Stocktwits remained in the ‘extremely bullish’ zone, amid ‘extremely high’ message volumes. NVAX was also among the top three trending tickers on the platform at the time of writing.<img src="https://news.stocktwits-cdn.com/NVAX_jpg_1f4183eedd.webp" alt="NVAX.jpg">One bullish user said that the stock is undervalued.<stembedurl>https://stocktwits.com/ejaXstoXX/message/642272237</stembedurl>Another user was bullish about Matrix-M’s market potential.<stembedurl>https://stocktwits.com/P38FTD/message/642271830</stembedurl>The stock has declined around 6% over the past year.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-ivf-stock-soaring-premarket/cmUum0oR4ap">INVO Fertility’s 350% Spike Puts Microcap IVF Stocks Back On Retail Radar</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, a medical syringe is displayed on a screen, and the logo of Novavax in the background. (Photo Illustration by Nikos Pekiaridis/SOPA Images/LightRocket via Getty Images)

Why NVAX Stock Is Popping Pre-Market – And What Does Pfizer Have To Do With It?

The company signed a licensing agreement with Pfizer, granting it non-exclusive rights to use Matrix-M adjuvant in up to two disease areas.

NVAX Stock Rises Pre-Market As Pfizer Licenses Its Vaccine Technology

<ul class="summary-bullets"><li>ANKTIVA is an Interleukin-15 (IL-15) receptor agonist that helps develop and activate key cells that work to destroy cancer cells.</li><li>The company presented an overview of the clinical status of its papillary disease program, including more than five years of follow-up data.</li><li>The data demonstrated strong bladder preservation outcomes.</li></ul>ImmunityBio (IBRX) shares rose 6% in pre-market trading on Tuesday after the United States Food and Drug Administration (FDA) outlined a pathway for resubmitting its supplemental biologics license application (sBLA) for ANKTIVA in Bacillus Calmette Guérin (BCG)-unresponsive papillary bladder cancer, without requesting new trials.&nbsp;The company said it recently met with the FDA for a Type B end-of-phase meeting to review data spanning over five years.<h2 class="st-heading-2">The FDA Meeting</h2>During the meeting, ImmunityBio presented more than five years of follow-up data supporting the papillary disease indication. Long-term results, published in The Journal of Urology, showed bladder cancer–specific survival of around 96% at three years, with median survival not yet reached.The data also demonstrated strong bladder preservation outcomes, with cystectomy avoidance rates of 92% at one year and 82% at three years, alongside a safety profile consistent with ANKTIVA’s currently approved use in carcinoma in situ (CIS).Based on these discussions, the FDA recommended that ImmunityBio submit additional information for further evaluation to potentially support a resubmission of the sBLA initially filed in 2025. The Agency did not request any new clinical trials.“We have completed the assembly and analysis of the requested additional information and will submit it within the next 30 days for the Agency’s review,” said Richard Adcock, President and CEO of ImmunityBio.ANKTIVA is an Interleukin-15 (IL-15) receptor agonist. IL-15 is an immune system protein that helps develop and activate key cells that work to destroy cancer cells. It is already commercially available in the U.S. for NMIBC CIS, with or without papillary tumors, and has received approvals in the U.K. and Saudi Arabia, as well as conditional approval in the European Union.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits for <a href="https://stocktwits.com/symbol/IBRX">IBRX</a> remained in the ‘extremely bullish’ territory over the past 24 hours, amid ‘extremely high’ message volumes. IBRX was among the top trending tickers on the platform at the time of writing.<img src="https://news.stocktwits-cdn.com/IBRX_jpg_704152379c.webp" alt="IBRX.jpg">One user laid out the potential triggers for the stock.<stembedurl>https://stocktwits.com/end2war/message/642249657</stembedurl>Over the past year, the stock has gained 85,% and year-to-date, it has added more than 173%.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-did-rapt-stock-surge-63-in-pre-market-today/cmUuK0vR4aO">Why Did RAPT Stock Surge 63% In Pre-Market Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, an ImmunityBio company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

IBRX Stock Extends Rally On FDA Feedback For ANKTIVA Bladder Cancer Filing

The company said it recently held end-of-phase talks with the United States Food and Drug Administration on its ANKTIVA application for treatment-resistant papillary bladder cancer.

This FDA Signal Is Powering IBRX Stock's Pre-Market Jump

<ul class="summary-bullets"><li>Morgan Stanley said the trends that led the space technology sector to outperform in 2025 are likely to carry over into 2026.</li><li>The brokerage firm also introduced an “Attractive industry view” for space technology through 2026.</li><li>Rocket Labs closed out 2025 with 21 successful Electron rocket launches.</li></ul>Rocket Lab USA Inc. (RKLB) drew investor interest with its shares rising 2.8% in pre-market trading on Friday, following a Morgan Stanley upgrade and a price target boost, driven by expectations of strong industry tailwinds in 2026.Morgan Stanley upgraded Rocket Lab to ‘Overweight’ from ‘Equal Weight’ and raised its price target to $105 from $67, according to The Fly. This represents a near 13% upside to the current share price of $93.2.RKLB stock is on track to open at an all-time high and was among the top trending tickers on Stocktwits at the time of writing.<h2 class="st-heading-2">What Did Morgan Stanley Say?</h2>The brokerage cast a bullish view on the space technology industry in 2026, adding that the trends that drove the sector's outperformance in 2025 are likely to carry over into 2026.Morgan Stanley also introduced an “Attractive industry view” for space technology through 2026, driven by higher launch cadences, new products, policy support, and market maturation. The firm cited improved risk/reward for the upgrades it made, including the Canada-based MDA Space.<h2 class="st-heading-2">Recent Developments</h2>Rocket Lab was among the top-performing satellite companies in 2025, with its stock more than tripling in value. It closed out the year with 21 successful Electron rocket launches and saw its revenue climb nearly 40% in the first three quarters. For the fourth quarter (Q4), the company expects revenue between $170 million and $180 million, representing 32% upside from the previous corresponding period, assuming the upper end of the range.However, the feather in its cap came in the form of a $816 million contract from the U.S. Space Development Agency last month. Rocket Labs will design and build 18 satellites for the Tracking Layer Tranche 3 program. It is the largest single contract in the company’s history.Rocket Lab’s first launch this year will take place from New Zealand on January 20.<h2 class="st-heading-2">Retail Reaction</h2>Some users were bullish, despite retail sentiment on Stocktwits remaining in ‘neutral’ territory over the past 24 hours.One saw a long-term play till 2030.<stembedurl>https://stocktwits.com/G_Unit2023/message/642018735</stembedurl>Another user simply said it would be a perfect weekend if the stock crossed $100.<stembedurl>https://stocktwits.com/Stockanizer/message/642017893</stembedurl>&nbsp;Read also:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/why-did-atos-stock-jump-10-in-pre-market-today/cmUlYPeR4Bc">Why Did ATOS Stock Jump 10% In Pre-Market Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com

In this photo illustration, a person holds a smartphone displaying the logo of Rocket Lab USA Inc.

RKLB Stock Is On Track For Record Open – Here’s What’s Driving The Rally 

Morgan Stanley upgraded Rocket Lab to ‘Overweight’ from ‘Equal Weight’ and raised its price target to $105 from $67, according to The Fly.

<ul class="summary-bullets"><li>The trial compares Bacillus Calmette-Guérin (BCG) therapy alone with BCG combined with ANKTIVA.</li><li>Preliminary analysis showed that ANKTIVA plus BCG significantly extended the duration of complete response in BCG-naïve cancer patients.</li><li>ImmunityBio plans to submit a biologics license application to the FDA by the end of 2026.</li></ul>ImmunityBio, Inc. (IBRX) shares jumped 24% in premarket trading on Friday after the company reported a faster than expected enrollment for its QUILT-2.005 bladder cancer drug trial.The company said that enrollment has surpassed internal expectations and is now more than 85% complete, with full enrollment of the planned study population expected by the second quarter of 2026.&nbsp;Based on current progress, ImmunityBio plans to submit a biologics license application to the U.S. Food and Drug Administration (FDA) by the end of 2026.“We look forward to the final accrual of this important registrational randomized trial in patients with BCG-naïve non-muscle-invasive bladder cancer, which represents a substantial proportion of newly diagnosed bladder cancer cases. The interim analysis is encouraging and consistent with findings in the approved BCG-unresponsive setting, where the duration of complete response has exceeded 47 months,” said Patrick Soon-Shiong, M.D., Founder, Executive Chairman, and Global Chief Medical and Scientific Officer of ImmunityBio.Based on current progress, ImmunityBio plans to submit a biologics license application to the FDA by the end of 2026.<h2 class="st-heading-2">What Is The Trial About?</h2>The QUILT-2.005 is a clinical trial for Bacillus Calmette-Guérin (BCG) naïve non-muscle-invasive bladder cancer (NMIBC) that compares standard BCG therapy alone versus BCG combined with ANKTIVA, an Interleukin-15 (IL-15) receptor agonist. IL-15 is an immune system protein that helps develop and activate key cells that work to destroy cancer cells.In 2023, the FDA requested an interim analysis of the randomized trial to evaluate the added benefit of ANKTIVA when combined with BCG, focusing on complete response rates and the durability of response versus BCG alone.The analysis showed that ANKTIVA plus BCG significantly extended the duration of complete response in BCG-naïve NMIBC patients. At six months, 85% of patients receiving the combination maintained a complete response, compared with 57% in the BCG-only group. At nine months, response rates were 84% with combination therapy versus 52% with BCG alone.<h2 class="st-heading-2">How Did Retail React?</h2>Retail sentiment for <a href="https://stocktwits.com/symbol/IBRX">IBRX</a> on Stocktwits remained in the ‘extremely bullish’ zone over the past 24 hours, amid ‘extremely high’ message volumes.<img src="https://news.stocktwits-cdn.com/IBRX_jpg_3d2f27a76b.webp" alt="IBRX.jpg">One user was bullish about the company’s potential.<stembedurl>https://stocktwits.com/Amit18/message/642024906</stembedurl>Another user saw the stock as a long-term runner.<stembedurl>https://stocktwits.com/LeftyT/message/642025351</stembedurl>Over the past year, the stock has gained more than 60%.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/rklb-stock-set-for-all-time-high-morgan-stanley-boost/cmUlAaBR4B7">RKLB Stock Is On Track For Record Open – Here’s What’s Driving The Rally</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Why IBRX Stock Is One Of The Biggest Pre-Market Movers Today 

The company said that enrollment for its randomized registrational QUILT-2.005 trial has surpassed internal expectations and is now more than 85% complete.

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